DENGUE VIRUS 3 GENOTYPE I (GI) LINEAGE 1 (L1) ISOLATES ELICIT DIFFERENTIAL CYTOPATHIC EFFECT WITH SYNCYTIUM FORMATION IN HUMAN GLIOBLASTOMA CELLS (U251)

Abstract Background Dengue virus (DENV) is a Flaviviridae member classified into four antigenically distinct serotypes (DENV 1, 2, 3, and 4) and further Black Walnut subdivided genotypes.DENV3 is subdivided into four or five genotypes, depending on the classification adopted.Despite their high genetic proximity, as revealed by phylogenetic complete

Abstract Triple-negative breast cancer (TNBC) patients have a poor prognosis and few treatment options.Mouse models of TNBC are important for development of new therapies, however, few mouse models represent the complexity of TNBC.Here, we develop a female TNBC murine model by mimicking two Mystery Minis common TNBC mutations with high co-occurrenc

Ena/VASP proteins are powerful actin polymerases that drive the processive elongation of actin filaments.Members of this protein family have been implicated in a variety of important cellular processes including axon guidance, cell migration and adhesion.However, the specific function of these proteins in macroendocytosis, comprising macropinocytos

Second order perturbed 2-D Heisenberg Hamiltonian model was employed to explain the magnetic properties of fcc and bcc structured ferromagnetic thin films with five to twenty spin layers.Magnetic energy versus azimuthal angle of spin was plotted to find the angle corresponding to maximum energy Blush and minimum energy.Hence magnetic easy and hard